R05CB03 - Carbocisteine |
Probably Not Porphyrinogenic |
PNP |
Rationale
Non-CYP metabolism. Absence of reported interactions with CYP-metabolised drugs indicate lack of capacity for CYP-induction or CYP-inhibition.
Chemical description
Modified amino acid, structurally related to cysteine.
Therapeutic characteristics
Mucolytic agent used to thin and loosen mucus in respiratory conditions. It is taken orally in doses up to 750 mg three times daily.
Published experience
No case reports found.
Ipnet drug reports
Uneventful use reported in 2 patients with acute porphyria.
Similar drugs
Explore alternative drugs in similar therapeutic classes
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Carbocysteine.
Brown DT. Drug Intell Clin Pharm. 1988; 22(7-8):603-8.
|
3046890 |
| Drug reference publications | ||
| 2. | DrugBank. Carbocisteine. Available from: https://go.drugbank.com/
Access Date: 2026-April-30 |
|
| 3. | Merative™ Micromedex® Drug Interaction Checking (electronic version). Ann Arbor, Michigan, USA: Merative. Available from: https://www.micromedexsolutions.com/
Access Date: 2026-April-30 |
|
| Drug interaction databases | ||
| 4. | Preston, C.L. (ed). Stockley’s Interaction Checker. London: Pharmaceutical Press. Available from: https://www.medicinescomplete.com/#/interactions/stockley
Access Date: 2026-April-30 |
|
| Summary of Product Characteristics | ||
| 5. | Summary of Product Characteristics (SmPC). Carbocisteine 375 mg Capsules. Flamingo Pharma (UK) Ltd. Date of revision of text: 24 January 2025. Available from: https://www.medicines.org.uk/emc/
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Tradenames
Availnex 
Acuphlem · Betaphlem · Bronchette · co-Flem · Flemgo · Flemlite · Flusin Mucuos · Lessmusec · Mucokleer · Mucolytic · Mucopan · Mucosolv · Mucospect 
Mucodyne 
Muco Rhinathiol · Siroxyl 
Actithiol · Cinfamucol Carbocisteina · Fluidin · Intermucol · Mucoactiol · Notus Mucolítico · Pectox · Pectox Forte · Viscoteína 
Lolimucin · Mucopront · Rhinathiol 
Broncolib · Carbocisteina · Coryfin · Fluifort · Glosid · Katarfluid · Kofituss · Lisomucil · Mucocis · Mucolase · Mucostar · Mucotreis · Recofluid · Solucis · Tusselim 
Fluidol · Rhinathiol 
gem · Maku · Pectorex 
Carbocisteine · Mucodyne · Mucodyne Paediatric 
Auropect · Flegamax · Flegmax Forte · Mucoflav · Mucopect · Mukolina · Pecto Drill · Pulnozin · Strepsils 
Bronquisol Flem · Bucoxolflem · Carbocisteina · Flemoxin · Mucosina 
Mucodyne 
Mucodin · Mucon Mucolytic · Mucopront · Rhinathiol · Scmc · Solmux 
Muco Rhinathiol · Siroxyl 
Benylin · Expudyne · Exputex · Mucotex · Viscolex · Xtex /5 
Fluditec 
Fluditec 
Fluditec 
Bronchobos · Bronles · Mucodyne 
Bronles · Karbocistein · Karbocistein Alpha 
Fenorin 
Loviscol · Mucodyne · Mucofan · Mucolex · Pulmoclase 
Carbocisteina 
Carbocisteine